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Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables Contains 6 Ig-like C2-type (immunoglobulin-like)

SKU: 10360402406

4.8
USD111.00 USD135.00

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Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables Contains 6 Ig-like C2-type (immunoglobulin-like)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Store: cgm.lt · Domain: cgm.lt

Description

Contains 6 Ig-like C2-type (immunoglobulin-like) domains

but their full length sequences have not been determined

|cofactor:Binds 1 Fe(3+) ion per subunit

thereby contributing to the inotropic response elicited in heart by beta-agonists

ensuring smooth filtration

Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables Contains 6 Ig-like C2-type (immunoglobulin-like)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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