PA26 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Three transcript variants encoding two

Three transcript variants encoding two different isoforms have been found for this gene

Mutations in this gene are associated with nail-patella syndrome

The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands

which is required for its IL12 binding activity

Mutations in TP53 are associated with a variety of human cancers

PA26 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Three transcript variants encoding twoSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized