Phospho-4E-BP1 (T69) Polyclonal Antibody, 50ul Gene Synthesis subcellular location:In epithelial cells

subcellular location:In epithelial cells

The protein localizes to the outer membrane of mitochondria

This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex

Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis

No expression was seen in adrenal NCI-H295A cells or in adrenal tissue

Phospho-4E-BP1 (T69) Polyclonal Antibody, 50ul Gene Synthesis subcellular location:In epithelial cellsEIF4EBP1 encodes one member of a family of translation repressor proteins. The eukaryotic translation initiation factor 4E binding protein 1 directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is