CSKI2 Polyclonal Antibody, 50ul Centrifugal Filter These heterogeneous aggregates consist of

These heterogeneous aggregates consist of 30-40 subunits| the alpha-A and alpha-B subunits have a 3:1 ratio

The encoded protein has been shown to interact with neurotrophin receptor

Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49)

It has also been identified as a structural protein for chromosomes

Mutations in this gene are associated with papillary renal cell carcinoma| hepatocellular carcinoma| and various head and neck cancers

CSKI2 Polyclonal Antibody, 50ul Centrifugal Filter These heterogeneous aggregates consist ofThis gene encodes a large protein that contains six ankyrin repeats, as well as a Src homology 3 (SH3) domain and two sterile alpha motif (SAM) domains, which may be involved in protein protein interactions. The C terminal portion of this protein is proline rich and contains a conserved region. A related protein interacts with calcium calmodulin dependent serine protein kinase (CASK). Alternative splicing results in multiple transcript variants.