TRIM27 Rabbit Polyclonal Antibody, 20ul Cell Biology Mutations and deletions at this

Mutations and deletions at this locus have been associated with severe mental retardation

The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane

DefectsF8 results in hemophilia A

exons 2 and 3 encode the alpha1 and alpha2 domain

CDK15 (Cyclin-Dependent Kinase 15) is a Protein Coding gene

TRIM27 Rabbit Polyclonal Antibody, 20ul Cell Biology Mutations and deletions at thisThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N terminus of this protein with the truncated C