IL-5R Alpha Polyclonal Antibody, 20ul[BT-AP04508] Organelle Studies GAS8 includes 11 exons spanning

GAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer

The protein encoded by this gene is structurally related to IL2R alpha

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

localizes to a region of the Y chromosome frequently deleted in infertile males

this protein does not interact with RASGAP

IL-5R Alpha Polyclonal Antibody, 20ul[BT-AP04508] Organelle Studies GAS8 includes 11 exons spanningThe protein encoded by IL5RA is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2 GM CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required