TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube This gene encodes a secreted

This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes

Allelic variants of this gene have been associated with autism and addiction vulnerability

Mutations in this gene have been associated with hereditary hemochromatosis type III

Nuclear receptor subfamily 3 group C member 1 is typically found in the cytoplasm

adult stem/progenitor cell regulation

TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube This gene encodes a secretedTransducin like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD repeats implicated in protein protein interaction. TLEs are transcriptional co repressors that bind to many transcription factors such as LEF1, Runx1, Oct 1, hepatocyte nuclear factor 3 as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as