HMX2 Polyclonal Antibody, 20ul Polyclonal Antibodies Dynactin binds to both microtubules

Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions

Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity)

PTM:Phosphorylated on tyrosine and serine/threonine

AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

CDC42 and RAC1

HMX2 Polyclonal Antibody, 20ul Polyclonal Antibodies Dynactin binds to both microtubulesThe protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss.