PRAS40(Phospho-Ser183) Rabbit Polyclonal Antibody, 20ul Monoclonal Antibody Preparation Required for chromatin and/or kinetochore

Required for chromatin and/or kinetochore dependent microtubule nucleation

Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates

This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity

Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus

K-12 substr

PRAS40(Phospho-Ser183) Rabbit Polyclonal Antibody, 20ul Monoclonal Antibody Preparation Required for chromatin and/or kinetochoreAKT1S1 is a proline rich substrate of AKT (MIM 164730) that binds 14 3 3 protein (see YWHAH MIM 113508) when phosphorylated (Kovacina et al. 2003