PABP4 Polyclonal Antibody, 50ul Modification Enzymes Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been found for this gene

Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B

This gene may be associated with tumor progression

This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4)

TJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family

PABP4 Polyclonal Antibody, 50ul Modification Enzymes Several alternatively spliced transcript variantsPoly(A) binding proteins (PABPs) bind to the poly(A) tail present at the 3 prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation induced T cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5 fold. PABPC4 contains 4 RNA binding domains and proline rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be