IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification and may play a role

and may play a role in the development of artherosclerosis and rheumatoid arthritis

cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits

releasing them into the nucleoplasm

Two alternative transcripts encoding the same protein have been described

This encoded protein acts preferentially as a receptor for NTN compared to its other family member

IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification and may play a roleIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.