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Chk2(Phospho Thr387) Polyclonal Antibody, 20ul General Lab Use Depletion of this protein in

SKU: 2087722291

4.6
SEK97.20 SEK146.20

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Chk2(Phospho Thr387) Polyclonal Antibody, 20ul General Lab Use Depletion of this protein inIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the

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Description

Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis

including release of gastrointestinal hormones

kidney and intestine and similar to aldolase C levels in brain and other nervous tissue

while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism

Two transcript variants encoding different isoforms have been found for PLD2

Chk2(Phospho Thr387) Polyclonal Antibody, 20ul General Lab Use Depletion of this protein inIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the

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