ANG I Polyclonal Antibody, 20ul[BT-AP06259] Protein Research also known as MPHOSPH9

also known as MPHOSPH9

The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA

|subcellular location:A significant proportion of isoform 2 localizes to mitochondria| it may be cleaved constitutively

Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36

using a separate promoter in an intron in the 3' region

ANG I Polyclonal Antibody, 20ul[BT-AP06259] Protein Research also known as MPHOSPH9The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that