AP-1 Polyclonal Antibody, 100ul[BT-AP00492] Cell Culture & Maintenance This PTP also suppresses JAK

This PTP also suppresses JAK kinases

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases

They also reduce the mitochondrial membrane potential in mammalian cells

and the counterbalancing phosphatase

Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression

AP-1 Polyclonal Antibody, 100ul[BT-AP00492] Cell Culture & Maintenance This PTP also suppresses JAKJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.