PI 3-kinase p85 Alpha Polyclonal Antibody, 50ul[BT-AP07139] Protein Post-translational Modification Protein phosphatase 2A holoenzymes are

Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A

These isoforms exhibit different expression pattern

CUL4A and COP1

The activation of this protein is dependent upon the binding of cytokines to their receptors

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PI 3-kinase p85 Alpha Polyclonal Antibody, 50ul[BT-AP07139] Protein Post-translational Modification Protein phosphatase 2A holoenzymes arePhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1