EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 50ul Pipette Holder 1 that encodes an orphan

1 that encodes an orphan G protein-coupled receptor

Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

in particular

TWEAK transcript is expressed broadly in many adult and fetal tissues

The protein encoded by this gene is secreted and is a member of the beta defensin protein family

EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 50ul Pipette Holder 1 that encodes an orphanThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.