NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Activity can be restored to

Activity can be restored to the latent form of PAI-1 through denaturation and renaturation

The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase

Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease

Inhibition of the encoded protein restores hemostasis in animal models of hemophilia

Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene

NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Activity can be restored toNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.