GRK 5 Polyclonal Antibody, 50ul Capsule Filter Several transcript variants encoding different

Several transcript variants encoding different isoforms have been described for GRK6

Polymorphisms in this gene may be associated with systemic sclerosis

acts by ubiquitinating SYK and promoting its proteasomal degradation

and a widespread distribution in the brain

two putative nuclear localization signals

GRK 5 Polyclonal Antibody, 50ul Capsule Filter Several transcript variants encoding differentGRK5 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. G protein coupled receptor kinase 5 phosphorylates the activated forms of G protein coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).