KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation This gene's protein is found

This gene's protein is found in the cytoplasm| yet it lacks the nuclear localization signals found in other subfamily members

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

• 3 acceleration level & 4 level deceleration

KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation This gene's protein is foundThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia