EI24 Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers E2F transcription factor 4 binds

E2F transcription factor 4 binds to all three of the tumor suppressor proteins pRB

Expression of this gene is induced by TGFBR1

a putative transmembrane domain

The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins

This gene is deleted in Williams-Beuren syndrome

EI24 Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers E2F transcription factor 4 bindsThis gene encodes a putative tumor suppressor and has higher expression in p53 expressing cells than in control cells and is an immediate early induction target of p53 mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24 a region frequently altered in cancers. Alternative splicing results in multiple transcript