Rb(Phospho Ser249) Polyclonal Antibody, 20ul Dry Bath It has been found to

It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis

The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels

NOLC1 (Nucleolar And Coiled-Body Phosphoprotein 1) is a Protein Coding gene

The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E)| which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs

An increase in apoC-III levels induces the development of hypertriglyceridemia

Rb(Phospho Ser249) Polyclonal Antibody, 20ul Dry Bath It has been found toThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.