AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis Consistent with this observation

Consistent with this observation

Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene

This gene is the putative transforming gene of avian sarcoma virus 17

and a cytoplasmic domain with predicted serine/threonine specificity

Alternatively spliced transcript variants encoding different isoforms have been found in GABRA4

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis Consistent with this observationAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with