NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation The encoded protein interacts with

The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes

is a E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage

SH3BGR (SH3 Domain Binding Glutamate Rich Protein) is a Protein Coding gene

implicated in a variety of cellular processes

MC5R encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation The encoded protein interacts withProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.