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p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development high-quality results every time

SKU: 2992719349

4.0
USD185.00 USD233.00

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p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development high-quality results every timeTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

high-quality results every time

Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1)

this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development

CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient

p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development high-quality results every timeTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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