Artn Polyclonal Antibody, 50ul Mammalian Expression Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase

Gene Ontology (GO) annotations related to this gene include chromatin binding and nucleosome binding

ovary and small intestin

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Artn Polyclonal Antibody, 50ul Mammalian Expression Multiple alternatively spliced transcript variantsThis gene encodes a secreted ligand of the glial cell line derived neurotrophic factor (GDNF) subfamily and TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer.