OTUB2 Polyclonal Antibody, 100ul Recombinant Protein Expression The alpha 6 beta 4

The alpha 6 beta 4 integrin may promote tumorigenesis

The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin

The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis

determination and differentiation

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

OTUB2 Polyclonal Antibody, 100ul Recombinant Protein Expression The alpha 6 beta 4OTUB2 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. OTU deubiquitinase, ubiquitin aldehyde binding 2 contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.