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ESX1 Rabbit Polyclonal Antibody, 20ul Oligo Pool Alternative splicing of PARK2 produces

SKU: 30856821977

4.4
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ESX1 Rabbit Polyclonal Antibody, 20ul Oligo Pool Alternative splicing of PARK2 producesThis gene encodes a dual function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N terminal fragment with a paired like homeodomain and a 20 kDa C terminal fragment with a proline rich domain. The C terminal fragment localizes to the cytoplasm while the N terminal fragment localizes exclusively to the nucleus. In contrast to human the mouse homolog has a novel PN PF motif in the C terminus and is paternally imprinted in

Store: cgm.lt · Domain: cgm.lt

Description

Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms

The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair

The zinc finger with KRAB and SCAN domains 5 contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation

MAPK3 and JNK

Antibodies to 4

ESX1 Rabbit Polyclonal Antibody, 20ul Oligo Pool Alternative splicing of PARK2 producesThis gene encodes a dual function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N terminal fragment with a paired like homeodomain and a 20 kDa C terminal fragment with a proline rich domain. The C terminal fragment localizes to the cytoplasm while the N terminal fragment localizes exclusively to the nucleus. In contrast to human the mouse homolog has a novel PN PF motif in the C terminus and is paternally imprinted in

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