SARM1 Polyclonal Antibody, 20ul Pasteur Pipets Mutations in THRB are known

Mutations in THRB are known to be a cause of generalized thyroid hormone resistance (GTHR)

This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene

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Tumor necrosis factor receptor superfamily member 3 plays a role in signalling during the development of lymphoid and other organs

The enzyme is responsible for the synthesis of histidyl-transfer RNA

SARM1 Polyclonal Antibody, 20ul Pasteur Pipets Mutations in THRB are knownWas initially reported to contain ARM repeats (PubMed: 11386760). Such repeats are however not predicted by any detection method.,Involved in innate immnune response. Acts as a negative regulator of TICAM1 TRIF dependent Toll like receptor signaling by inhibiting induction of TLR3 and TLR4 dependent genes. Specifically blocks TICAM1 TRIF dependent transcription factor activation and gene induction, without affecting the MYD88 dependent pathway or non