GGT2 Rabbit Polyclonal Antibody, 20ul ADME In addition to its role

In addition to its role in the PDE complex| the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia

Among its related pathways are Endocytosis and Notch Signaling Pathways

are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal

Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4)

Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system

GGT2 Rabbit Polyclonal Antibody, 20ul ADME In addition to its roleGGT2 belongs to the gamma glutamyltransferase (GGT; EC 2. 3. 2. 2) gene family. GGT is a membrane bound extracellular enzyme that cleaves gamma glutamyl peptide bonds in glutathione and other peptides and transfers the gamma glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al. 2008