Rat Amphiregulin, AREG ELISA Kit, 96T Gene Synthesis Studies of FLASH protein suggested

Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor

Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity)

stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines

CASP4 or CASP5 in response to canonical

The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E)| which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs

Rat Amphiregulin, AREG ELISA Kit, 96T Gene Synthesis Studies of FLASH protein suggestedLigand of the EGF receptor EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.