Mre11(Phospho-Ser676) Rabbit Polyclonal Antibody, 100ul Vessels It may also play a

It may also play a role in cell survival by suppressing apoptosis

and cancer growth and metastasis

The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome

and has been shown to localize in the lysosomes

The protein localizes to the nucleus and is down-regulated in some cancer cell lines

Mre11(Phospho-Ser676) Rabbit Polyclonal Antibody, 100ul Vessels It may also play aThis gene encodes a nuclear protein involved in homologous recombination telomere length maintenance and DNA double strand break repair. By itself the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA