TIN2 Polyclonal Antibody, 50ul Supplements In mice| it has been

In mice| it has been shown to be essential for correct myelination in the peripheral nervous system

This gene encodes a small salivary mucin

This protein influences processing of amyloid-beta precursor protein

and activating different transcription factors

This gene product binds to and inactivates p38 and SAPK/JNK

TIN2 Polyclonal Antibody, 50ul Supplements In mice| it has beenTINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an