Human Alpha-2B Adrenergic Receptor, ADRA2B ELISA Kit, 96T miRNA / siRNA Synthesis Does not undergo receptor internalization

Does not undergo receptor internalization following ligand binding (PubMed: 7476993)

Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis

Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone

This gene encodes the cartilage intermediate layer protein (CILP)

68-KD (on chromosome 17)

Human Alpha-2B Adrenergic Receptor, ADRA2B ELISA Kit, 96T miRNA / siRNA Synthesis Does not undergo receptor internalizationAlpha 2 adrenergic receptors mediate the catecholamine induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p tyramine = phenylephrine > serotonin > p synephrine p octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol >