Nibrin Polyclonal Antibody, 20ul[BT-AP06021] Measuring Instruments Alternate splicing results in multiple

Alternate splicing results in multiple transcript variants

These defects can result in a lifelong bleeding tendency

GPR35 (G protein-coupled receptor 35) is a 309 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family

The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity

Mutations in NRXN1 are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia

Nibrin Polyclonal Antibody, 20ul[BT-AP06021] Measuring Instruments Alternate splicing results in multipleMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.