Rtn-3 Monoclonal Antibody, 100ul[BT-MCA1110] Isothermal Amplification Cystic fibrosis transmembrane conductance regulator

Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene

and has two modified domains that are thought to have lost their calcium binding capability

and spindle poles

Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D

This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence

Rtn-3 Monoclonal Antibody, 100ul[BT-MCA1110] Isothermal Amplification Cystic fibrosis transmembrane conductance regulatorThis gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta amyloid converting enzyme 1 (BACE1), and the production of amyloid beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid beta, suggesting that reticulon proteins are negative modulators of BACE1 in