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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging and a C-terminal cytoplasmic domain

SKU: 3478439338

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USD141.00 USD180.00

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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging and a C-terminal cytoplasmic domainTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

and a C-terminal cytoplasmic domain

is due to mutations in the ALMS1 gene

CDCA7 (cell division cycle associated 7) was identified as a c-Myc responsive gene

This kinase has also been found to bind and activate protein kinase C-related kinase 2| which suggests its involvement in a regulated signaling process

guanine nucleotide exchange factors (GEFs)

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging and a C-terminal cytoplasmic domainTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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