p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Transcription factor E2F4 encoded by

Transcription factor E2F4 encoded by E2F4 is a member of the E2F family of transcription factors

most notably the t(9|22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR| MIM:151410)

This gene is thought to be intronless

This gene is clustered with other MAGED genes on chromosome Xp11

The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes

p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Transcription factor E2F4 encoded byTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni