ATX3L Rabbit Polyclonal Antibody, 20ul Cell Biology Expression of this gene decreases

Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients

This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine

NBPF4 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

is conserved in chimpanzee

It is a caspase-3 substrate

ATX3L Rabbit Polyclonal Antibody, 20ul Cell Biology Expression of this gene decreasesThis intronless gene may be a pseudogene (PMID: 11450850). This gene is similar to the multi exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado Joseph disease.