NACAD Polyclonal Antibody, 100ul sgRNA Library Construction the human ortholog of Rudhira

the human ortholog of Rudhira is 98% identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23

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and its expression and activation is associated with transformation and tumorigenesis

The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis

An important paralog of this gene is JMJD7-PLA2G4B

NACAD Polyclonal Antibody, 100ul sgRNA Library Construction the human ortholog of RudhiraMay prevent inappropriate targeting of non secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).