CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes Three alternatively spliced variants encoding

Three alternatively spliced variants encoding different isoforms have been described for this gene

Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons

Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene

suggesting a distinct role for this antizyme in spermiogenesis

The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA

CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes Three alternatively spliced variants encodingDDIT3 encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. DNA damage inducible transcript 3 functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.