IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Additional splice variants have been

Additional splice variants have been described

tissue specificity:Overexpressed in psoriasis

Contains 2 RING-type zinc fingers

the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity

As with many proteins

IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Additional splice variants have beenIKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.