Fes Polyclonal Antibody, 50ul Cell Transfection DCLK2 encodes a member of

DCLK2 encodes a member of the protein kinase superfamily and the doublecortin family

Alternative splicing results in multiple transcript variants encoding distinct isoforms

This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor

Although this gene was isolated as a transforming gene from a melanoma cell line

but accumulates progressively throughout the S phase

Fes Polyclonal Antibody, 50ul Cell Transfection DCLK2 encodes a member ofFES encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor