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GFAP Polyclonal Antibody, 100ul Monoclonal Antibodies The encoded protein can phosphorylate

SKU: 41014547532

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GFAP Polyclonal Antibody, 100ul Monoclonal Antibodies The encoded protein can phosphorylateGFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

The encoded protein can phosphorylate myelin basic protein and histone in vitro

|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a small and a large subunit

The protein encoded by this gene is a small GTPase of the Rho-subfamily| which regulates signaling pathways that control diverse cellular functions including cell morphology| migration| endocytosis and cell cycle progression

Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases

which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones

GFAP Polyclonal Antibody, 100ul Monoclonal Antibodies The encoded protein can phosphorylateGFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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