Glypican-5 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Gene copy number variations in

Gene copy number variations in the human chromosomal region 1q21

Variation at this gene has been observed in patients with absorptive hypercalciuria

Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia

Alternatively spliced transcript variants encoding the same protein have been identified

Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination

Glypican-5 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Gene copy number variations inCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.