JIP-1 Polyclonal Antibody, 100ul Immune Cell Analysis The protein encoded by KLF7

The protein encoded by KLF7 (Kruppel like factor 7)is a member of the Kruppel-like transcriptional regulator family

An important paralog of this gene is CDK14

Several transcript variants encoding different isoforms have been found for VIPR1

but activates transcription when Ras is present

May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death

JIP-1 Polyclonal Antibody, 100ul Immune Cell Analysis The protein encoded by KLF7MAPK8IP1 encodes a regulator of the pancreatic beta cell function. C Jun amino terminal kinase interacting protein 1 is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). C Jun amino terminal kinase interacting protein 1 has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells.