LGR5 Polyclonal Antibody, 100ul Cell Culture Plates Mutations in this gene are

Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder

a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus

MAPK activation cascades mediate various physiologic processes| including cellular proliferation| apoptosis| differentiation| and stress responses (summary by Patterson et al

MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair

gene synthesis and cloning

LGR5 Polyclonal Antibody, 100ul Cell Culture Plates Mutations in this gene areThe protein encoded by this gene is a leucine rich repeat containing receptor (LGR) and member of the G protein coupled, 7 transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have