Beclin-1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Homeobox protein ARX contains two

Homeobox protein ARX contains two conserved domains

Several transcript variants encoding different isoforms have been found for PPP1R12A

It has been shown to mediate the immunosuppressive signal of interleukin 10

The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A

Mutations in this gene have been associated with bone marrow failure syndrome 2

Beclin-1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Homeobox protein ARX contains twoThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.