TXND2 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos A translocation involving this gene

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

Expressed in various cancer cell lines

there is no correlation between the repeat number and the disease

it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain

The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms

TXND2 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos A translocation involving this geneProbably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,Contains 1 thioredoxin domain.,subcellular location: