CBX2 Polyclonal Antibody, 50ul CellSafe™ The high mobility group nucleosomal

The high mobility group nucleosomal binding domain 2 encoded by HMGN2 binds nucleosomal DNA and is associated with transcriptionally active chromatin

Mice lacking this gene are more susceptible to bacterial infection than wild type mice

Customizable user setting program with up to 6 sequential steps

however| it does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats

Contains 2 protein kinase domains

CBX2 Polyclonal Antibody, 50ul CellSafe™ The high mobility group nucleosomalCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms