p57 Monoclonal Antibody, 100ul Plasma Both subunits are members of

Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160)

This gene encodes alpha-enolase

Mutations in STXBP1 have been associated with infantile epileptic encephalopathy-4

Alternatively spliced transcript variants encoding distinct isoforms have been found for GOSR1

The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis

p57 Monoclonal Antibody, 100ul Plasma Both subunits are members ofThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.